Key features: • Expanded first chapter on levels of echocardiography. • New sections on COVID-19, cardio-oncology, multivalve disease, and specialist valve clinics. • Incorporation of new international guidelines, grading criteria and normal data. • Guide to how cardiac CT and magnetic resonance can compliment echocardiography. • Reformatted text and extra diagrams and tables to improve understanding.

Key features: • Expanded first chapter on levels of echocardiography. • New sections on COVID-19, cardio-oncology, multivalve disease, and specialist valve clinics. • Incorporation of new international guidelines, grading criteria and normal data. • Guide to how cardiac CT and magnetic resonance can compliment echocardiography. • Reformatted text and extra diagrams and tables to improve understanding.

Blackbirds is a dark fantasy tabletop role-playing game, Powered by ZWEIHAENDER RPG. The gods failed us. The powerful betrayed us. Rise to meet your fate. Twelve years of war have ravaged the kingdoms of Erebos, where the great battle that would decide the fate of all has been waged. . .and lost. Now, the lights of civilization are going out. Swells of refugees have taken to the roads, desperate to find homes far from all the suffering. New constellations twinkle in the vault of the night, only to disappear if scrutinized for too long. Creatures of long-forgotten folklore once again stalk the countryside. It is a time of ill omens and unlikely heroes. BLACKBIRDS RPG is set in a dark fantasy world where a cabal of power-hungry Oligarchs has stolen godhood. Their horrific act rent the fabric of reality, allowing corrupt magic to undermine the world's natural order. And, soon, the Oligarchs themselves will return to the mortal plane and remake it as they desire.

CBT for Managing Non-cardiac Chest Pain is an evidence-based guide and workbook for clinicians working with people with non-cardiac chest pain (NCCP). NCCP affects around 25-30% of people in the UK, USA, and Europe and is associated with high levels of health care use and compromised quality of life. This is the first book to describe a treatment programme to fill the gap in care for patients. The authors have developed and researched a novel approach that demonstrates how physiological, cognitive, behavioural and social factors all contribute to the negative experience of chest pain. With the help of exercises and downloadable handouts for the patient, the book aims to provide the necessary information and clinical skills and approaches for clinicians to use in health care settings. CBT for Managing Non-cardiac Chest Pain will appeal to anyone involved in the care of patients with NCCP, including nurses; general practitioners; cardiologists; acute medical physicians and psychologists.

CBT for Managing Non-cardiac Chest Pain is an evidence-based guide and workbook for clinicians working with people with non-cardiac chest pain (NCCP). NCCP affects around 25-30% of people in the UK, USA, and Europe and is associated with high levels of health care use and compromised quality of life. This is the first book to describe a treatment programme to fill the gap in care for patients. The authors have developed and researched a novel approach that demonstrates how physiological, cognitive, behavioural and social factors all contribute to the negative experience of chest pain. With the help of exercises and downloadable handouts for the patient, the book aims to provide the necessary information and clinical skills and approaches for clinicians to use in health care settings. CBT for Managing Non-cardiac Chest Pain will appeal to anyone involved in the care of patients with NCCP, including nurses; general practitioners; cardiologists; acute medical physicians and psychologists.

The birth and evolution of our solar system is a tantalizing mystery that may one day provide answers to the question of human origins. From Dust to Life tells the remarkable story of how the celestial objects that make up the solar system arose from common beginnings billions of years ago, and how scientists and philosophers have sought to unravel this mystery down through the centuries, piecing together the clues that enabled them to deduce the solar system's layout, its age, and the most likely way it formed. Drawing on the history of astronomy and the latest findings in astrophysics and the planetary sciences, John Chambers and Jacqueline Mitton offer the most up-to-date and authoritative treatment of the subject available. They examine how the evolving universe set the stage for the appearance of our Sun, and how the nebulous cloud of gas and dust that accompanied the young Sun eventually became the planets, comets, moons, and asteroids that exist today. They explore how each of the planets acquired its unique characteristics, why some are rocky and others gaseous, and why one planet in particular--our Earth--provided an almost perfect haven for the emergence of life. From Dust to Life is a must-read for anyone who desires to know more about how the solar system came to be. This enticing book takes readers to the very frontiers of modern research, engaging with the latest controversies and debates. It reveals how ongoing discoveries of far-distant extrasolar planets and planetary systems are transforming our understanding of our own solar system's astonishing history and its possible fate.

We are in Ireland and it's an awfully long time ago. Centuries and centuries. The country is supposed to have gone Christian, but there's still magic in the air, salmon in the rivers, berries in the bushes, druids in the forest, a Worm in the lake, fairy music in the distance. Manchan's mother wants to make a monk of Manchan. Manchan most emphatically does not want to be made a monk of. He'd rather sing songs with his father, or go fishing with his friend, Pagan-of the-Six-Toes, or go charging through the forest with his pet pig, Muck, or go bare-back riding over the bog on the chieftain's mad ram, Balor. Anything fun or adventurous or magical, and absolutely nothing to do with turnips, penance, prayers, monks and chanting. Poor Manchan! The more he mucks about having fun, the more his mother is determined to tame him.

Although statistical design is one of the oldest branches of statistics, its importance is ever increasing, especially in the face of the data flood that often faces statisticians. It is important to recognize the appropriate design, and to understand how to effectively implement it, being aware that the default settings from a computer package can easily provide an incorrect analysis. The goal of this book is to describe the principles that drive good design, paying attention to both the theoretical background and the problems arising from real experimental situations. Designs are motivated through actual experiments, ranging from the timeless agricultural randomized complete block, to microarray experiments, which naturally lead to split plot designs and balanced incomplete blocks.

John Chambers turns his attention to R, the enormously successful open-source system based on the S language. His book guides the reader through programming with R, beginning with simple interactive use and progressing by gradual stages, starting with simple functions. More advanced programming techniques can be added as needed, allowing users to grow into software contributors, benefiting their careers and the community. R packages provide a powerful mechanism for contributions to be organized and communicated. This is the only advanced programming book on R, written by the author of the S language from which R evolved.

Newton's heretical writings on theology, spirituality, alchemy, and prophecy, uncovered and analyzed. Isaac Newton (1643-1727) is still regarded by the world as the greatest scientist who ever lived. He invented calculus, discovered the binomial theorem, explained the rainbow, built the first reflecting telescope, and explained the force of gravity. In his famous masterpiece, Principia Mathematica, he described the mechanics of the physical universe with unimagined precision, proving the cosmos was put together according to laws. The perfection of these laws implied a perfect legislator. To Newton, they were proof that God existed. At the same time Newton was writing Principia Mathematica, he was writing a twin volume that he might have called, had it been completed, Principia Theologia--Principles of Theology. This other masterpiece of Newton, kept secret because of the heresies it contained, consists of thousands of essays providing equation-incisive answers to the spiritual questions that have plagued mankind through the ages. Examining Newton's secret writings, John Chambers shows how his brilliance extended into alchemy, spirituality, the search for lost continents such as Atlantis, and a quest to uncover the "corrupted texts" that were rife in the Bibles of his time. Although he was a devout Christian, Newton's work on the Bible was focused not on restoring the original Jewish and Christian texts but on rediscovering the one true religion that existed prior to the Flood of Noah, when science and spirituality were one. The author shows that a single thread runs through Newton's metaphysical explorations: He is attempting to chart the descent of man's soul from perfection to the present day. The author also examines Newton's alternate timeline of ancient history and his study of prophecy through the Book of Revelations, including his prediction of an Apocalypse in the year 2060 followed by a radically transformed world. He shows that Newton's great hope was that these writings would provide a moral compass for humanity as it embarked upon the great enterprise that became our technological world.

The birth and evolution of our solar system is a tantalizing mystery that may one day provide answers to the question of human origins. This book tells the remarkable story of how the celestial objects that make up the solar system arose from common beginnings billions of years ago, and how scientists and philosophers have sought to unravel this mystery down through the centuries, piecing together the clues that enabled them to deduce the solar system's layout, its age, and the most likely way it formed.

Drawing on the history of astronomy and the latest findings in astrophysics and the planetary sciences, John Chambers and Jacqueline Mitton offer the most up-to-date and authoritative treatment of the subject available. They examine how the evolving universe set the stage for the appearance of our Sun, and how the nebulous cloud of gas and dust that accompanied the young Sun eventually became the planets, comets, moons, and asteroids that exist today. They explore how each of the planets acquired its unique characteristics, why some are rocky and others gaseous, and why one planet in particular--our Earth--provided an almost perfect haven for the emergence of life.

From Dust to Life is a must-read for anyone who desires to know more about how the solar system came to be. This enticing book takes readers to the very frontiers of modern research, engaging with the latest controversies and debates. It reveals how ongoing discoveries of far-distant extrasolar planets and planetary systems are transforming our understanding of our own solar system's astonishing history and its possible fate.